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Structure of 851202-96-5
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This benzo[b][1,4]oxazine scaffold integrates a carboxylic acid at the 7-position, offering a rigid, electron-rich heterocyclic platform for medicinal chemistry. The fused ring system enhances metabolic stability and facilitates hydrogen bonding in target engagement. Its bench-stable, moisture-tolerant nature simplifies handling in synthesis workflows.
3,4-Dihydro-2H-benzo[b][1,4]oxazine-7-carboxylic acid serves as a versatile scaffold for medicinal chemistry and synthetic organic applications. The carboxylic acid functionality enables direct derivatization via amide coupling, esterification, or salt formation, while the fused oxazine ring system provides structural rigidity and favorable pharmacokinetic properties. Bench-stable and compatible with standard protecting group strategies, it facilitates efficient access to heterocyclic libraries and API intermediates through well-established transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: