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Structure of 851386-33-9
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5,6-Difluoro-3-pyridinecarboxylic acid features a pyridine core with strategically positioned fluorine atoms enhancing electron deficiency and metabolic stability. This substitution pattern improves membrane permeability and enables direct incorporation into bioactive scaffolds. The carboxylic acid group facilitates conjugation via amide or ester linkages, supporting use in medicinal chemistry and materials synthesis.
5,6-Difluoro-3-pyridinecarboxylic acid serves as a versatile building block for medicinal chemistry and agrochemical synthesis, enabling direct incorporation of fluorinated pyridine motifs into bioactive molecules. Its ortho-fluorine substituents enhance metabolic stability and modulate electronic properties, while the carboxylic acid group facilitates amide coupling, esterification, and metal-mediated transformations. The compound exhibits excellent bench stability and compatibility with standard purification techniques, supporting scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: