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Structure of 851386-40-8
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4-Chloro-2,5-difluoropyridine is a fluorinated pyridine derivative featuring complementary halogen substituents that enable selective cross-coupling reactions. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds and serves as a key building block in the synthesis of bioactive molecules.
4-Chloro-2,5-difluoropyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The chlorine and fluorine substituents offer complementary sites for selective functionalization, facilitating the construction of complex heterocyclic scaffolds with enhanced metabolic stability. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: