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Structure of 851861-61-5
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3-(3,5-Dichlorophenyl)piperidine is a sterically defined piperidine derivative featuring a dichlorinated phenyl ring at the 3-position. This configuration imparts enhanced lipophilicity and metabolic stability, enabling efficient integration into bioactive molecules. The compound serves as a key scaffold in medicinal chemistry for targeting CNS receptors and modulating pharmacokinetic profiles.
3-(3,5-Dichlorophenyl)piperidine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard coupling and functionalization reactions. Its electron-deficient aryl group enhances metabolic stability, while the piperidine core provides a basic nitrogen for salt formation and hydrogen bonding. The compound exhibits good bench stability and is compatible with common purification methods, facilitating integration into multi-step syntheses of pharmaceutical candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: