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Structure of 852204-67-2
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Dimethyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)phosphonate delivers a boronate-functionalized aryl phosphonate unit with enhanced stability and solubility in aqueous-organic mixtures. This bench-stable reagent integrates readily into Suzuki-Miyaura coupling protocols, enabling efficient C–C bond formation under mild conditions. The tetramethyl-substituted dioxaborolane moiety resists protodeboronation, while the phosphonate group provides orthogonal reactivity for downstream functionalization.
Dimethyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)phosphonate serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylborolane moiety ensures excellent stability and shelf life, while the phosphonate group enables selective functionalization in complex molecule synthesis. This reagent facilitates efficient C–C bond formation under mild conditions, offering high chemoselectivity and compatibility with diverse functional groups, making it well-suited for pharmaceutical and agrochemical scaffold development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: