Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Ethyl 5-hydroxy-1H-pyrazole-3-carboxylate

  • CAS No. 85230-37-1

  • Cat. No. CS-0062453
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 5-hydroxy-1H-pyrazole-3-carboxylate|CS-0062453

Structure of 85230-37-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 85230-37-1
  • Cat. No. CS-0062453
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O₃
  • Molecular Weight 156.14
  • Synonym(s) 1H-Pyrazole-3-carboxylic acid, 5-hydroxy-, ethyl ester
  • SMILES O=C(C1=NNC(O)=C1)OCC

Description

Ethyl 5-hydroxy-1H-pyrazole-3-carboxylate features a hydroxyl group at the 5-position and an ester-functionalized pyrazole core, enabling direct derivatization in synthetic sequences. This bench-stable scaffold integrates readily into heterocyclic libraries and supports efficient functionalization via oxidation or coupling reactions under mild conditions.

Application

Ethyl 5-hydroxy-1H-pyrazole-3-carboxylate serves as a versatile building block for heterocyclic synthesis, enabling efficient access to substituted pyrazole scaffolds via electrophilic functionalization or coupling reactions. The pendant hydroxyl group offers a handle for derivatization, while the ester functionality supports further transformations under standard conditions. Its bench-stable nature and compatibility with common reaction protocols make it well-suited for medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • In-stock
      Hydrazine monohydrochloride|CS-W019806
      2644-70-4
    • Sodium (Z)-1,4-diethoxy-1,4-dioxobut-2-en-2-olate|CS-0139103
      88330-76-1
    • ~91%
    • In-stock
      Ethyl 5-hydroxy-1H-pyrazole-3-carboxylate|CS-0062453
      85230-37-1

    References

    • F. HOFFMANN-LA ROCHE AG Patent: WO2004/74257 A1, 2004 ; Location in patent: Page 26; 37; 38 ; WO 2004/074257 A1
  • Route2

    References

    • Ochi; Miyasaka Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 4 p. 1228 - 1234
  • Route3
    • null|null
      64-17-5
    • null|null
      687-00-3
    • ~72%
    • In-stock
      Ethyl 5-hydroxy-1H-pyrazole-3-carboxylate|CS-0062453
      85230-37-1

    References

    • Martins, Marcos A. P.; Pereira, Claudio M. P.; Zimmermann, Nilo E. K.; Moura, Sidnei; Sinhorin, Adilson P.; Cunico, Wilson; Zanatta, Nilo; Bonacorso, Helio G.; Flores, Alex C. F. Synthesis, 2003 , # 15 p. 2353 - 2357

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   75.21
  • LogP   0.292
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 85230-37-1 sigma85230-37-1 manufacturer85230-37-1 price85230-37-1 structure85230-37-1 SDSbuy 85230-37-185230-37-1 supplier85230-37-1 uses85230-37-1 molecular weightprice of 85230-37-185230-37-1 chemical name formula of 85230-37-1
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label