Lot numbers can be found on the outside label of a product:
Ethyl 1-methyl-1H-pyrazole-4-carboxylate
-
CAS No. 85290-80-8
- Cat. No. CS-0037203
- Purity≥96%
- MDL No.None
*For research and further manufacturing use only, not for direct human use.
Structure of 85290-80-8
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 85290-80-8
- Cat. No. CS-0037203
- Purity ≥96%
- MDL No. None
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₇H₁₀N₂O₂
- Molecular Weight 154.17
- Synonym(s) 1H-Pyrazole-4-carboxylic acid, 1-ethyl-, methyl ester
- SMILES CCOC(=O)C1=CN(C)N=C1
Description
Ethyl 1-methyl-1H-pyrazole-4-carboxylate features a pyrazole core with complementary electron-rich and ester functionalities, enabling direct integration into diverse heterocyclic syntheses. This bench-stable reagent facilitates efficient access to biologically relevant scaffolds through straightforward derivatization.
Application
Ethyl 1-methyl-1H-pyrazole-4-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyrazole-based scaffolds through standard functional group transformations. Its stable ethyl ester and methyl-substituted pyrazole core offer excellent compatibility with palladium-catalyzed cross-coupling reactions, nucleophilic substitutions, and reductive amination protocols. The compound exhibits favorable bench stability and simplifies purification, making it well-suited for iterative medicinal chemistry campaigns and process-scale applications.
Synthesis
-
Route1
-
80370-42-9 -
60-34-4
- ~99%
-
In-stock
85290-80-8
References
-
ARRAY BIOPHARMA INC.; ANDREWS, Steven Wade; BLAKE, James F.; BRANDHUBER, Barbara J.; KERCHER, Timothy; WINSKI, Shannon L. Patent: WO2014/78325 A1, 2014 ; Location in patent: Paragraph 00663 ;
-
-
Route2
-
In-stock
37622-90-5 -
74-88-4
- ~84%
-
In-stock
85290-80-8
References
-
F. HOFFMANN-LA ROCHE AG Patent: WO2003/106459 A1, 2003 ; Location in patent: Page 115; 156 ;
-
-
Route3
-
540-80-7
- ~%
-
In-stock
85290-80-8
References
-
Monsanto Company Patent: US5498630 A1, 1996 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 44.12
- LogP 0.5968
- H_Acceptors 4
- H_Donors 0
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Ethyl 1-methyl-1H-pyrazole-4-carboxylate sigmaEthyl 1-methyl-1H-pyrazole-4-carboxylate manufacturerEthyl 1-methyl-1H-pyrazole-4-carboxylate priceEthyl 1-methyl-1H-pyrazole-4-carboxylate structureEthyl 1-methyl-1H-pyrazole-4-carboxylate SDSbuy Ethyl 1-methyl-1H-pyrazole-4-carboxylateEthyl 1-methyl-1H-pyrazole-4-carboxylate supplierEthyl 1-methyl-1H-pyrazole-4-carboxylate usesEthyl 1-methyl-1H-pyrazole-4-carboxylate molecular weightprice of Ethyl 1-methyl-1H-pyrazole-4-carboxylateEthyl 1-methyl-1H-pyrazole-4-carboxylate chemical name formula of Ethyl 1-methyl-1H-pyrazole-4-carboxylate