Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-Methyl-1,5,6,7-tetrahydro-4H-indazol-4-one

  • CAS No. 85302-16-5

  • Cat. No. CS-0130154
  • Molecule weight150.18
  • Purity≥97%
  • MDL No.MFCD00930489

*For research and further manufacturing use only, not for direct human use.

1-Methyl-1,5,6,7-tetrahydro-4H-indazol-4-one|CS-0130154

Structure of 85302-16-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 85302-16-5
  • Cat. No. CS-0130154
  • Purity ≥97%
  • MDL No. MFCD00930489
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O
  • Molecular Weight 150.18
  • Synonym(s) 1-Methyl-6,7-dihydro-1H-indazol-4(5H)-one
  • SMILES O=C1C2=C(N(C)N=C2)CCC1

Description

1-Methyl-1,5,6,7-tetrahydro-4H-indazol-4-one is a bench-stable heterocyclic scaffold featuring a masked carbonyl and nitrogen-rich core. This electron-deficient indazolone integrates readily into medicinal chemistry campaigns, offering enhanced solubility and metabolic stability. Its modular structure enables efficient derivatization for targeted bioactive molecule design.

Application

1-Methyl-1,5,6,7-tetrahydro-4H-indazol-4-one serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to indazole-based scaffolds. Its stable tetrahydroindazolone core exhibits favorable functional group tolerance and facilitates downstream derivatization via nucleophilic substitution or coupling reactions. The molecule's bench stability and ease of purification support scalable synthesis workflows, making it a practical choice for the construction of bioactive compounds.

Synthesis

  • Route1

    References

    • Alinezhad, Heshmatollah; Tajbakhsh, Mahmood; Zare, Mahboobeh Journal of Fluorine Chemistry, 2011 , vol. 132, # 11 p. 995 - 1000
  • Route2
    • In-stock
      2-((Dimethylamino)methylene)cyclohexane-1,3-dione|CS-0145586
      85302-07-4
    • null|null
      60-34-4
    • ~90%
    • In-stock
      1-Methyl-1,5,6,7-tetrahydro-4H-indazol-4-one|CS-0130154
      85302-16-5

    References

    • Peet, Norton P.; LeTourneau, Michael E. Heterocycles, 1991 , vol. 32, # 1 p. 41 - 72
  • Route3
    • In-stock
      2-((Dimethylamino)methylene)cyclohexane-1,3-dione|CS-0145586
      85302-07-4
    • null|null
      60-34-4
    • ~63%
    • In-stock
      1-Methyl-1,5,6,7-tetrahydro-4H-indazol-4-one|CS-0130154
      85302-16-5
    • null|null
      85302-22-3

    References

    • Schenone, Pietro; Mosti, Luisa; Menozzi, Giulia Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1355 - 1361

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   34.89
  • LogP   0.9391
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 85302-16-5 sigma85302-16-5 manufacturer85302-16-5 price85302-16-5 structure85302-16-5 SDSbuy 85302-16-585302-16-5 supplier85302-16-5 uses85302-16-5 molecular weightprice of 85302-16-585302-16-5 chemical name formula of 85302-16-5
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label