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Structure of 854044-51-2
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This imidazole derivative features a bromine atom at the 2-position and a trimethylsilylethoxymethyl group at C1, paired with a carbonitrile at C4. The silyl ether moiety offers enhanced stability and selective reactivity in synthetic transformations. Designed for use in advanced heterocyclic synthesis, it facilitates efficient coupling reactions under mild conditions.
2-Bromo-1-(2-trimethylsilylethoxymethyl)imidazole-4-carbonitrile serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted imidazoles via palladium-catalyzed cross-coupling. The trimethylsilyl ether group provides robust protection under standard reaction conditions and can be selectively cleaved post-functionalization. Its bromo and nitrile functionalities offer orthogonal reactivity, facilitating sequential transformations. Bench-stable and readily purified by flash chromatography, it supports scalable synthesis of complex scaffolds relevant to medicinal chemistry and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: