1-Methyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid

Name: 1-Methyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 854405-75-7
Cat. No. CS-0047143
Molecule weight166.18
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-Methyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid|CS-0047143

Structure of 854405-75-7

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 854405-75-7
Cat. No. CS-0047143
Purity ≥98%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₀N₂O₂
Molecular Weight 166.18
Synonym(s) 1-Methyl-1,4,5,6-tetrahydro-cyclopentapyrazole-3-carboxylic acid
SMILES O=C(C1=NN(C)C2=C1CCC2)O

Description

1-Methyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid features a rigid, electron-deficient heterocyclic core that integrates readily into bioactive scaffolds. This bench-stable carboxylic acid derivative offers enhanced solubility and metabolic stability in medicinal chemistry applications, enabling efficient coupling in peptide synthesis and fragment-based drug discovery workflows.

Application

1-Methyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard coupling and functionalization reactions. Its carboxylic acid group facilitates amide bond formation and derivatization under mild conditions, while the tetrahydrocyclopenta[c]pyrazole core exhibits good bench stability and compatibility with diverse functional groups. This compound functions effectively in parallel synthesis campaigns and process development workflows.

Synthesis

Route1
- 120-92-3
- ~%
- In-stock
  
  854405-75-7
References
- v. Auwers; Noll Justus Liebigs Annalen der Chemie, 1938 , vol. 536, p. 97,108
Route2
- In-stock
  
  39163-39-8
- 302-15-8
- ~%
- In-stock
  
  854405-75-7
- In-stock
  
  129560-01-6
References
- v. Auwers; Noll Justus Liebigs Annalen der Chemie, 1938 , vol. 536, p. 97,108

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 55.12
LogP 0.607
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Key Words

854405-75-7 sigma854405-75-7 manufacturer854405-75-7 price854405-75-7 structure854405-75-7 SDSbuy 854405-75-7854405-75-7 supplier854405-75-7 uses854405-75-7 molecular weightprice of 854405-75-7854405-75-7 chemical name formula of 854405-75-7

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-Methyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carboxylic acid

CAS No. 854405-75-7

Recommended Products