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CS-W001157 4
Total: USD 88.00

Potassium (3-acetylphenyl)trifluoroborate

  • CAS No. 854906-74-4

  • Cat. No. CS-0190063
  • Molecule weight226.05
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Potassium (3-acetylphenyl)trifluoroborate|CS-0190063

Structure of 854906-74-4

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General Information

  • CAS No. 854906-74-4
  • Cat. No. CS-0190063
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇BF₃KO
  • Molecular Weight 226.05
  • Synonym(s) None
  • SMILES CC(=O)C1=CC(=CC=C1)[B-](F)(F)F.[K+]

Description

Potassium (3-acetylphenyl)trifluoroborate delivers a bench-stable, moisture-tolerant boronate handle for cross-coupling reactions. The para-acetyl group enhances reactivity in Suzuki-Miyaura processes while maintaining compatibility with diverse functional groups. This reagent integrates seamlessly into complex molecular architectures under standard conditions.

Application

Potassium (3-acetylphenyl)trifluoroborate serves as a stable, bench-ready boronate building block for palladium-catalyzed cross-coupling reactions. It facilitates efficient Suzuki-Miyaura coupling with aryl and heteroaryl halides, enabling direct access to biaryl scaffolds with retained acetyl functionality. The trifluoroborate group offers enhanced hydrolytic stability and predictable reactivity, simplifying purification and integration into multi-step synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   -1.0524
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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