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Structure of 856965-66-7
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4,5-Dichloropyridin-2(1H)-one features a rigid, electron-deficient pyridinone core with two chlorine substituents at the 4 and 5 positions, enabling selective coupling reactions. This scaffold integrates readily into bioactive molecules due to its stability under standard conditions and compatibility with diverse synthetic transformations.
4,5-Dichloropyridin-2(1H)-one serves as a versatile building block in medicinal chemistry, enabling efficient construction of substituted pyridine scaffolds. Its dichloro substitution pattern facilitates selective nucleophilic aromatic substitution, allowing for facile functionalization at C4 or C5 positions. The enolized carbonyl moiety enhances reactivity in coupling reactions and contributes to favorable solubility and purification characteristics, making it well-suited for bench-scale synthesis and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: