5-Hydroxy-N-methylpicolinamide

Name: 5-Hydroxy-N-methylpicolinamide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 859538-76-4
Cat. No. CS-0456491
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Hydroxy-N-methylpicolinamide|CS-0456491

Structure of 859538-76-4

Size

Price

Quantity

* Please select Quantity before adding items.

Description

5-Hydroxy-N-methylpicolinamide features a hydroxyl group at the 5-position of the pyridine ring, paired with a methylated amide functionality. This combination enhances solubility and metabolic stability while maintaining strong hydrogen-bonding capacity. The molecule serves as a key scaffold in bioactive compound design, particularly in kinase inhibitor and CNS-targeted lead optimization.

Application

5-Hydroxy-N-methylpicolinamide serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds through standard amide coupling and electrophilic substitution reactions. Its hydroxyl and N-methylpyridine functionalities offer orthogonal reactivity for late-stage functionalization, while demonstrating excellent bench stability and compatibility with common purification methods.

General Information

CAS No. 859538-76-4
Cat. No. CS-0456491
Purity ≥98%
MDL No. None
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₈N₂O₂
Molecular Weight 152.15
Synonym(s) 5-hydroxy-N-methylpyridine-2-carboxamide
SMILES CNC(=O)C1=NC=C(C=C1)O

Computational Chemistry Data

TPSA 62.22
LogP 0.1468
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302+H312+H332-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Amide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

5-Hydroxy-N-methylpicolinamide sigma5-Hydroxy-N-methylpicolinamide manufacturer5-Hydroxy-N-methylpicolinamide price5-Hydroxy-N-methylpicolinamide structure5-Hydroxy-N-methylpicolinamide SDSbuy 5-Hydroxy-N-methylpicolinamide5-Hydroxy-N-methylpicolinamide supplier5-Hydroxy-N-methylpicolinamide uses5-Hydroxy-N-methylpicolinamide molecular weightprice of 5-Hydroxy-N-methylpicolinamide5-Hydroxy-N-methylpicolinamide chemical name formula of 5-Hydroxy-N-methylpicolinamide

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Hydroxy-N-methylpicolinamide

CAS No. 859538-76-4

Recommended Products