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CS-W001157 4
Total: USD 88.00

Dibenzo[b,d]furan-2-ol

  • CAS No. 86-77-1

  • Cat. No. CS-0270357
  • Molecule weight184.19
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Dibenzo[b,d]furan-2-ol|CS-0270357

Structure of 86-77-1

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General Information

  • CAS No. 86-77-1
  • Cat. No. CS-0270357
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₈O₂
  • Molecular Weight 184.19
  • Synonym(s) 2-Hydroxydibenzofuran
  • SMILES C1=CC=C2C(=C1)C3=C(C=CC(=C3)O)O2

Description

Dibenzo[b,d]furan-2-ol features a rigid, planar polycyclic scaffold with a phenolic hydroxyl group at the 2-position, enabling hydrogen bonding and enhancing solubility in polar solvents. This structural motif supports its use in constructing functional materials and bioactive compounds through directed derivatization.

Application

Dibenzo[b,d]furan-2-ol serves as a versatile building block for oxygenated heterocyclic scaffolds, enabling direct functionalization at the phenolic position. Its stability under standard synthetic conditions and compatibility with palladium-catalyzed cross-coupling reactions facilitate access to biaryl architectures. The molecule functions effectively in electrophilic substitution and serves as a key intermediate in the synthesis of advanced pharmaceutical candidates and functional materials.

Synthesis

  • Route1
    • In-stock
      2-Nitrobenzofuran|CS-0156003
      33094-66-5
    • null|null
      54125-02-9
    • ~81%
    • In-stock
      Dibenzo[b,d]furan-2-ol|CS-0270357
      86-77-1

    References

    • Della Rosa, Claudia D.; Sanchez, Juan P.; Kneeteman, Maria N.; Mancini, Pedro M.E. Tetrahedron Letters, 2011 , vol. 52, # 18 p. 2316 - 2319
  • Route2
    • null|null
      20928-01-2
    • ~%
    • In-stock
      Dibenzo[b,d]furan-2-ol|CS-0270357
      86-77-1

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 14 p. 4316 - 4319
  • Route3
    • 2-Methoxydibenzo[b,d]furan|CS-0951583
      20357-70-4
    • ~98%
    • In-stock
      Dibenzo[b,d]furan-2-ol|CS-0270357
      86-77-1

    References

    • Majetich, George; Zhang, Yong; Wheless, Karen Tetrahedron Letters, 1994 , vol. 35, # 47 p. 8727 - 8730

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   33.37
  • LogP   3.2916
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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