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CS-W001157 4
Total: USD 88.00

2,4-Dihydroxyquinoline

  • CAS No. 86-95-3

  • Cat. No. CS-W020079
  • Molecule weight161.16
  • Purity≥95%
  • MDL No.MFCD00006744

*For research and further manufacturing use only, not for direct human use.

2,4-Dihydroxyquinoline|CS-W020079

Structure of 86-95-3

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General Information

  • CAS No. 86-95-3
  • Cat. No. CS-W020079
  • Purity ≥95%
  • MDL No. MFCD00006744
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇NO₂
  • Molecular Weight 161.16
  • Synonym(s) 2,4-Quinolinediol;4-Hydroxycarbostyril
  • SMILES O=C1NC2=C(C=CC=C2)C(O)=C1

Description

2,4-Dihydroxyquinoline features a fused heterocyclic core bearing two phenolic hydroxyl groups at the 2- and 4-positions, enhancing its ability to engage in hydrogen bonding and metal coordination. This structural motif imparts strong chelating capacity and electronic modulation, making it valuable in ligand design for catalytic systems and bioactive molecule scaffolds.

Application

2,4-Dihydroxyquinoline serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its ortho-diol motif offers enhanced solubility and hydrogen-bonding capacity, facilitating interactions with biological targets. The compound exhibits bench stability and compatibility with common protecting group strategies, supporting efficient synthesis of complex scaffolds in drug discovery workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   53.09
  • LogP   1.2337
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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