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Structure of 860585-01-9
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1-Chloro-3-iodo-2-methoxybenzene features a strategically positioned methoxy group that enhances solubility and modulates electronic properties. The ortho-methoxy substituent stabilizes the aromatic ring, while the flanking chloro and iodo groups enable selective cross-coupling reactions under mild conditions. This compound serves as a key intermediate in the synthesis of functionalized biaryls and pharmaceutical scaffolds.
1-Chloro-3-iodo-2-methoxybenzene serves as a versatile ortho-disubstituted aryl building block for palladium-catalyzed cross-coupling reactions. The chlorine and iodine functionalities enable sequential or selective transformations, while the methoxy group provides electronic modulation and enhanced solubility. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient construction of complex biaryl architectures in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: