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CS-W001157 4
Total: USD 88.00

Methyl (E)-3-(1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylate

  • CAS No. 86163-17-9

  • Cat. No. CS-0459211
  • Molecule weight312.28
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl (E)-3-(1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylate|CS-0459211

Structure of 86163-17-9

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General Information

  • CAS No. 86163-17-9
  • Cat. No. CS-0459211
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₆N₂O₇
  • Molecular Weight 312.28
  • Synonym(s) (E)-5-(2-CARBOMETHOXYVINYL)-2'-DEOXYURIDINE
  • SMILES O[C@H]1C[C@H](N2C(NC(C(/C=C/C(OC)=O)=C2)=O)=O)O[C@@H]1CO

Synthesis

  • Route1

    References

    • Rong; Soloway Nucleosides and Nucleotides, 1994 , vol. 13, # 9 p. 2021 - 2034
  • Route2

    References

    • Hirota, Kosaku; Isobe, Yoshiaki; Kitade, Yukio; Maki, Yoshifumi Synthesis, 1987 , # 5 p. 495 - 496
  • Route3
    • null|null
      76772-94-6
    • null|null
      292638-85-8
    • ~40%
    • Methyl (E)-3-(1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylate|CS-0459211
      86163-17-9

    References

    • Hassan, Mohamed E. Recueil des Travaux Chimiques des Pays-Bas, 1986 , vol. 105, # 1 p. 30 - 32

Safety Information

Download SDS
GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   130.85
  • LogP   -1.6365
  • H_Acceptors   8
  • H_Donors   3
  • Rotatable_Bonds   4

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