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CS-W001157 4
Total: USD 88.00

(11bR)​-2,​6-​Bis([1,​1'-​biphenyl]​-​4-​yl)​-​8,​9,​10,​11,​12,​13,​14,​15-​octahydro-​4-​hydroxy-4-​oxide-dinaphtho[2,​1-​d:1',​2'-​f]​[1,​3,​2]​dioxaphosphepin

  • CAS No. 861909-35-5

  • Cat. No. CS-0093374
  • Molecule weight660.74
  • Purity≥97%
  • MDL No.MFCD31747032

*For research and further manufacturing use only, not for direct human use.

(11bR)​-2,​6-​Bis([1,​1'-​biphenyl]​-​4-​yl)​-​8,​9,​10,​11,​12,​13,​14,​15-​octahydro-​4-​hydroxy-4-​oxide-dinaphtho[2,​1-​d:1',​2'-​f]​[1,​3,​2]​dioxaphosphepin|CS-0093374

Structure of 861909-35-5

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General Information

  • CAS No. 861909-35-5
  • Cat. No. CS-0093374
  • Purity ≥97%
  • MDL No. MFCD31747032
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₄H₃₇O₄P
  • Molecular Weight 660.74
  • Synonym(s) None
  • SMILES O=P1(O)OC2=C(C3=C(CCCC4)C4=CC(C5=CC=C(C6=CC=CC=C6)C=C5)=C3O1)C7=C(CCCC7)C=C2C8=CC=C(C9=CC=CC=C9)C=C8

Description

This sterically encumbered phosphine oxide features a rigid, octahydro-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin core with two biphenyl substituents at the 2,6-positions. The (11bR) configuration and hydroxy-4-oxide functionality confer enhanced stability and controlled reactivity, enabling precise coordination in catalytic systems.

Application

(11bR)-2,6-Bis([1,1'-biphenyl]-4-yl)-8,9,10,11,12,13,14,15-octahydro-4-hydroxy-4-oxide-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin functions as a chiral phosphine oxide scaffold with enhanced steric and electronic tuning for transition-metal catalysis. Its bench-stable, octahydroxanthylenic core enables robust performance in asymmetric cross-coupling reactions, particularly in Pd-catalyzed processes requiring high enantioselectivity and functional group tolerance.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315
Precautionary Statements : P264-P280-P302+P352-P362

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Computational Chemistry Data

  • TPSA   55.76
  • LogP   11.6508
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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