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Structure of 863868-19-3
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4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile delivers a boronate handle flanked by electron-withdrawing chloro and cyano groups, enabling efficient cross-coupling under standard conditions. This bench-stable reagent integrates readily into complex molecular architectures via palladium-catalyzed reactions.
4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The nitrile group provides orthogonal functionality for downstream transformations, while the sterically protected boronate ester ensures excellent bench stability and compatibility with diverse reaction conditions. This reagent enables efficient construction of biaryl scaffolds in medicinal chemistry and materials science workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: