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Structure of 863868-36-4
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This boronate ester features a 3,5-difluorophenyl group attached to a tetramethyl-substituted dioxaborolane ring, offering enhanced stability and moisture tolerance. The electron-deficient aryl moiety enables efficient coupling in Suzuki-Miyaura reactions under standard conditions.
2-(3,5-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. Its tetramethyl-substituted dioxaborolane ring enhances air and moisture stability while maintaining high reactivity in palladium-catalyzed coupling with aryl halides and triflates. The 3,5-difluorophenyl moiety offers predictable electronic effects and orthogonal functional group tolerance, enabling efficient construction of biaryl scaffolds prevalent in pharmaceutical and agrochemical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: