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Structure of 863868-37-5
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This boronate ester features a 2,6-difluorophenyl group attached to a tetramethyl-1,3,2-dioxaborolane scaffold, delivering enhanced stability and reactivity in cross-coupling processes. The electron-withdrawing difluoro substitution improves coupling efficiency while maintaining bench-stable handling characteristics under standard conditions.
2-(2,6-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. Its ortho-difluorophenyl moiety enables efficient coupling with aryl halides and triflates, offering enhanced reactivity and metabolic stability in complex molecule synthesis. The tetramethyl-substituted dioxaborolane ring ensures high chemical stability, minimal protodeboronation, and straightforward purification—ideal for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: