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Structure of 864235-83-6
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Fmoc-NH-ethyl-SS-propionic acid features a disulfide-linked ethyl spacer flanked by propionic acid and Fmoc-protected amine functionalities. This bifunctional reagent enables site-specific conjugation in peptide synthesis, where the cleavable disulfide bond facilitates controlled release under reducing conditions. The Fmoc group ensures orthogonal protection during solid-phase assembly, while the ethyl-SS bridge provides stability and efficient coupling efficiency.
Fmoc-NH-ethyl-SS-propionic acid serves as a versatile cysteine-derived building block for disulfide-linked peptide conjugates and antibody-drug conjugates. Its Fmoc group enables efficient solid-phase peptide synthesis, while the disulfide bond provides site-specific cleavage under reducing conditions. The ethyl-SS-propionic acid spacer offers enhanced stability and controlled release, facilitating purification and enabling robust synthetic workflows in bioconjugation applications.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: