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Structure of 864292-37-5
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2,4-Dichloro-7-fluoro-6-methoxyquinazoline features a highly functionalized quinazoline core with orthogonal reactivity enabled by chlorine, fluorine, and methoxy substituents. This electron-deficient scaffold integrates readily into pharmaceutical intermediates, offering robust stability under standard conditions and compatibility with palladium-catalyzed coupling reactions.
2,4-Dichloro-7-fluoro-6-methoxyquinazoline serves as a versatile building block in medicinal chemistry, enabling efficient construction of quinazoline-based scaffolds. Its electrophilic chlorine and fluorine substituents facilitate nucleophilic substitution reactions under mild conditions, while the methoxy group enhances solubility and modulates electronic properties. The compound exhibits excellent bench stability and is compatible with standard coupling protocols, making it ideal for the synthesis of kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: