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Structure of 864770-82-1
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tert-Butyl 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate delivers a boronate-functionalized indazole scaffold with enhanced stability and solubility. This bench-stable reagent integrates readily into Suzuki-Miyaura coupling protocols, enabling efficient C–C bond formation under mild conditions. The tetramethyl-substituted dioxaborolane moiety ensures high functional group tolerance and compatibility with diverse reaction environments.
tert-Butyl 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate serves as a versatile boron-containing building block for Suzuki-Miyaura coupling reactions. The indazole core provides a rigid, bioactive scaffold commonly found in pharmaceuticals, while the tert-butyl ester offers stability and ease of deprotection. The pinacol boronate group enables efficient cross-coupling under mild conditions, with excellent functional group tolerance and bench stability, making it ideal for iterative synthesis in medicinal chemistry and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: