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CS-W001157 4
Total: USD 88.00

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hex-5-enoic acid

  • CAS No. 865352-21-2

  • Cat. No. CS-W006331
  • Purity≥97%
  • MDL No.MFCD17215631

*For research and further manufacturing use only, not for direct human use.

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hex-5-enoic acid|CS-W006331

Structure of 865352-21-2

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General Information

  • CAS No. 865352-21-2
  • Cat. No. CS-W006331
  • Purity ≥97%
  • MDL No. MFCD17215631
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₁NO₄
  • Molecular Weight 351.40
  • Synonym(s) Fmoc-(2R)-2-AMINO-5-HEXENOIC ACID
  • SMILES C=CCC[C@H](C(O)=O)NC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O

Description

This fluoren-9-ylmethoxycarbonyl-protected amino acid features a chiral (R)-configuration and a conjugated enoic acid side chain, enabling efficient incorporation into peptide sequences. The C-terminal alkene facilitates downstream functionalization via cross-coupling or cycloaddition reactions. Bench-stable under standard conditions, this derivative supports streamlined synthesis of bioactive peptides and complex molecular architectures.

Application

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hex-5-enoic acid serves as a valuable chiral building block for peptide synthesis and medicinal chemistry. Its (R)-configured amino acid moiety, protected with the robust Fmoc group, enables efficient coupling reactions with minimal racemization. The terminal alkenyl functionality offers versatility for further functionalization via cross-coupling or cyclization strategies, while the Fmoc group ensures excellent bench stability and ease of purification in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   3.9445
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   7

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