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Structure of 86639-52-3
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N-palmitoyl-D-erythro-sphingosylphosphorylcholine (16:0 SM (d18:1/16:0)) has been used as a standard for the quantitation of sphingolipidmetabolites. It has also been used for the quantification of lipids in green fluorescence protein (GFP) and fatty acid transport protein 4 (FATP4) cells using electrospray ionization tandem mass spectrometry (ESI-MS/MS). It may be used in liposomes to measureostreolysinA (OlyA) binding todeterminethe effects ofphosphatidylcholines(PCs) onsphingomyelin(SM)/cholesterol interactions.
SN-38 serves as a potent topoisomerase I inhibitor and is the active metabolite of irinotecan, widely utilized in anticancer drug development. Its structure features a camptothecin core with critical lactone and hydroxyl functionalities essential for target binding. The compound enables direct evaluation of pharmacophore activity in preclinical studies and functions as a key reference standard in the synthesis and optimization of camptothecin-based therapeutics.
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GHS Pictogram :
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GHS No : GHS07,GHS08
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Signal Word : Danger
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H360-H372
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Precautionary Statements : P201-P202-P260-P264-P270-P280-P301+P310-P308+P313-P314-P330-P405-P501
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Lot numbers can be found on the outside label of a product: