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CS-W001157 4
Total: USD 88.00

(3aS,4S,6aR)-4-Methoxytetrahydrofuro[3,4-b]furan-2(3H)-one

  • CAS No. 866594-60-7

  • Cat. No. CS-0150981
  • Molecule weight158.15
  • Purity≥97%
  • MDL No.MFCD10698799

*For research and further manufacturing use only, not for direct human use.

(3aS,4S,6aR)-4-Methoxytetrahydrofuro[3,4-b]furan-2(3H)-one|CS-0150981

Structure of 866594-60-7

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General Information

  • CAS No. 866594-60-7
  • Cat. No. CS-0150981
  • Purity ≥97%
  • MDL No. MFCD10698799
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀O₄
  • Molecular Weight 158.15
  • Synonym(s) FURO[3,4-B]FURAN-2(3H)-ONE, TETRAHYDRO-4-METHOX
  • SMILES CO[C@@H]1[C@H]2CC(=O)O[C@H]2CO1

Description

This tetrahydrofuranone scaffold features a methoxy group at the 4-position, enhancing solubility and metabolic stability. The fused furan ring system imparts rigidity, enabling precise stereocontrol in synthetic transformations. This structural motif serves as a key building block in natural product synthesis and medicinal chemistry applications.

Application

(3aS,4S,6aR)-4-Methoxytetrahydrofuro[3,4-b]furan-2(3H)-one serves as a versatile chiral building block for the synthesis of bioactive heterocycles. Its rigid fused ring system provides stereochemical control in downstream transformations, while the methoxy and lactone functionalities enable selective derivatization. The compound exhibits excellent bench stability and facilitates efficient functional group interconversions in standard organic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   44.76
  • LogP   -0.0792
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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