N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(R)-2'-(dimethylamino)[1,1'-binaphthalen]-2-yl]thiourea

Name: N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(R)-2'-(dimethylamino)[1,1'-binaphthalen]-2-yl]thiourea
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 866940-63-8
Cat. No. CS-0091915
Purity≥95%
MDL No.MFCD27920533

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(R)-2'-(dimethylamino)[1,1'-binaphthalen]-2-yl]thiourea|CS-0091915

Structure of 866940-63-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

This thiourea features a chiral binaphthyl moiety paired with electron-deficient trifluoromethyl aryl groups, enabling strong hydrogen-bonding interactions in asymmetric catalysis. The (R)-configured binaphthyl unit imparts high enantioselectivity, while the trifluoromethyl substituents enhance both stability and binding affinity.

Application

N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(R)-2'-(dimethylamino)[1,1'-binaphthalen]-2-yl]thiourea serves as a chiral, sterically hindered thiourea catalyst that enables enantioselective transformations in asymmetric synthesis. Its trifluoromethylated aryl group enhances electron-withdrawing character and solubility, while the binaphthyl scaffold provides robust chirality transfer. The dimethylamino substituent fine-tunes hydrogen-bonding basicity, facilitating substrate activation in organocatalytic reactions. This compound demonstrates bench stability and compatibility with standard purification methods, making it suitable for iterative optimization in catalytic asymmetric processes.

General Information

CAS No. 866940-63-8
Cat. No. CS-0091915
Purity ≥95%
MDL No. MFCD27920533
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃₁H₂₃F₆N₃S
Molecular Weight 583.59
Synonym(s) N-[3,5-bis(trifluoromethyl)phenyl]-N'-[(1R)-2'-(dimethylamino)[1,1'-binaphthalen]-2-yl]- Thiourea
SMILES S=C(NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)NC2=C(C3=C(C=CC=C4)C4=CC=C3N(C)C)C5=CC=CC=C5C=C2

Computational Chemistry Data

TPSA 27.3
LogP 9.5725
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 4

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H413
Precautionary Statements : P264-P270-P330

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Key Words

866940-63-8 sigma866940-63-8 manufacturer866940-63-8 price866940-63-8 structure866940-63-8 SDSbuy 866940-63-8866940-63-8 supplier866940-63-8 uses866940-63-8 molecular weightprice of 866940-63-8866940-63-8 chemical name formula of 866940-63-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(R)-2'-(dimethylamino)[1,1'-binaphthalen]-2-yl]thiourea

CAS No. 866940-63-8

Recommended Products