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Structure of 869901-52-0
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4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)pyridine features a boronate ester group integrated with a pyridine heterocycle, enabling efficient cross-coupling reactions under mild conditions. The dimethyl-substituted dioxaborinane moiety enhances stability and moisture tolerance, while the electron-deficient pyridine ring facilitates selective functionalization in complex molecular architectures. This reagent streamlines the construction of biaryl systems in medicinal chemistry and materials science applications.
4-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)pyridine serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. Its sterically protected dioxaborinane moiety enhances air and moisture stability, enabling reliable coupling with aryl, heteroaryl, and vinyl halides. The pyridine core provides a versatile scaffold for constructing biologically relevant heterocycles, with excellent functional group tolerance and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: