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CS-W001157 4
Total: USD 88.00

Fmoc-3-Ala(5-thiazoyl)-OH

  • CAS No. 870010-07-4

  • Cat. No. CS-0439435
  • Molecule weight394.44
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Fmoc-3-Ala(5-thiazoyl)-OH|CS-0439435

Structure of 870010-07-4

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General Information

  • CAS No. 870010-07-4
  • Cat. No. CS-0439435
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₁₈N₂O₄S
  • Molecular Weight 394.44
  • Synonym(s) None
  • SMILES C(OC(N[C@@H](CC1=CN=CS1)C(O)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Description

Fmoc-3-Ala(5-thiazoyl)-OH features a 5-thiazoyl-modified alanine residue with a fluorenylmethoxycarbonyl (Fmoc) protecting group, enabling direct incorporation into peptide chains. The thiazoyl moiety imparts enhanced solubility and stability under standard coupling conditions. This derivative serves as a key building block for synthesizing bioactive peptides containing sulfur-rich motifs.

Application

Fmoc-3-Ala(5-thiazoyl)-OH serves as a versatile building block for peptide synthesis, enabling site-specific incorporation of a 5-thiazoyl-modified alanine residue. The Fmoc group ensures orthogonal protection for amine-directed coupling, while the thiazole moiety imparts enhanced rigidity and potential hydrogen-bonding capacity. This derivative exhibits excellent bench stability, facilitates straightforward purification, and functions reliably in standard solid-phase and solution-phase protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   88.52
  • LogP   3.6775
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   6

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