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Structure of 870062-76-3
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6-Chloro-5-fluoropyridin-3-ol features a trifunctional pyridine core bearing chlorine, fluorine, and hydroxyl groups at strategic positions. This electron-deficient heterocycle integrates readily into pharmaceutical scaffolds, offering enhanced metabolic stability and directional reactivity in cross-coupling processes. The hydroxyl group enables direct derivatization or hydrogen bonding interactions in target binding.
6-Chloro-5-fluoropyridin-3-ol serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. Its ortho-halogenated pyridinol scaffold offers excellent stability and compatibility with diverse reaction conditions, facilitating the construction of complex heterocyclic frameworks. The molecule's defined electronic profile enhances regioselective transformations, making it ideal for synthesizing API candidates and advanced intermediates in drug discovery workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: