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Structure of 870459-90-8
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This boronate moiety features a trifluoromethylpyridine scaffold, delivering enhanced stability and electron-deficient character. It enables efficient cross-coupling under standard conditions, pairing effectively with diverse partners in Suzuki-Miyaura reactions. The pendant pyridine ring facilitates directional coordination and improves solubility in polar media.
(4-(Trifluoromethyl)pyridin-2-yl)boronic acid serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. Its trifluoromethylpyridine core provides enhanced metabolic stability and modulated electronic properties, making it valuable in medicinal chemistry. The boronic acid functionality offers reliable reactivity in Suzuki-Miyaura coupling under standard conditions, with good bench stability and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: