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Structure of 870704-14-6
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2-Fluoro-5-methylbenzene-1-sulfonyl chloride features a fluorinated aromatic ring paired with a methyl group and a reactive sulfonyl chloride moiety. This combination enables efficient coupling in electrophilic functionalization, particularly in the synthesis of sulfonamide derivatives. The compound exhibits enhanced stability under standard bench conditions and facilitates selective derivatization in complex molecular architectures.
2-Fluoro-5-methylbenzene-1-sulfonyl chloride serves as a versatile sulfonylating agent for the introduction of a fluorinated, methyl-substituted benzene sulfonate group. It facilitates efficient formation of sulfonamide and sulfonate derivatives under mild conditions, with good bench stability and compatibility across diverse functional groups. Its reactivity profile supports applications in medicinal chemistry and process development, particularly in constructing bioactive heterocyclic scaffolds and modulating solubility in API candidates.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: