2,4-Dichloropyrimidine-5-carbaldehyde

Name: 2,4-Dichloropyrimidine-5-carbaldehyde
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 871254-61-4
Cat. No. CS-D0296
Molecule weight176.99
Purity≥97%
MDL No.MFCD11112096

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,4-Dichloropyrimidine-5-carbaldehyde|CS-D0296

Structure of 871254-61-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 871254-61-4
Cat. No. CS-D0296
Purity ≥97%
MDL No. MFCD11112096
Storage -20°C, stored under nitrogen, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₂Cl₂N₂O
Molecular Weight 176.99
Synonym(s) 5-Pyrimidinecarboxaldehyde, 2,4-dichloro-
SMILES O=CC1=CN=C(Cl)N=C1Cl

Description

2,4-Dichloropyrimidine-5-carbaldehyde features a reactive aldehyde group flanked by two electron-withdrawing chlorine atoms, enabling efficient coupling reactions in heterocyclic synthesis. This bench-stable scaffold integrates readily into pharmaceutical intermediates and functional materials.

Application

2,4-Dichloropyrimidine-5-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds through nucleophilic substitution and condensation reactions. The aldehyde group facilitates direct functionalization or derivatization, while the dichloropyrimidine core offers high reactivity toward amines and thiols under mild conditions. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for modular synthesis of kinase inhibitors and other bioactive compounds.

Synthesis

Route1
- In-stock
  
  4394-85-8
- In-stock
  
  36082-50-5
- ~73%
- In-stock
  
  871254-61-4
References
- ABBOTT LABORATORIES; WOLLER, Kevin R.; CURTIN, Michael L.; FRANK, Kristine E.; JOSEPHSOHN, Nathan S.; LI, Biqin C.; WISHART, Neil Patent: WO2011/156698 A2, 2011 ; Location in patent: Page/Page column 52 ; WO 2011/156698 A2
Route2
- In-stock
  
  36082-50-5
- 68-12-2
- ~27%
- In-stock
  
  871254-61-4
References
- Ding, Qingjie; Jiang, Nan; Roberts, John Lawson Patent: US2005/277655 A1, 2005 ; Location in patent: Page/Page column 15 ;

Safety Information

Download SDS

GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 42.85
LogP 1.5959
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Aldehyde

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

2,4-Dichloropyrimidine-5-carbaldehyde sigma2,4-Dichloropyrimidine-5-carbaldehyde manufacturer2,4-Dichloropyrimidine-5-carbaldehyde price2,4-Dichloropyrimidine-5-carbaldehyde structure2,4-Dichloropyrimidine-5-carbaldehyde SDSbuy 2,4-Dichloropyrimidine-5-carbaldehyde2,4-Dichloropyrimidine-5-carbaldehyde supplier2,4-Dichloropyrimidine-5-carbaldehyde uses2,4-Dichloropyrimidine-5-carbaldehyde molecular weightprice of 2,4-Dichloropyrimidine-5-carbaldehyde2,4-Dichloropyrimidine-5-carbaldehyde chemical name formula of 2,4-Dichloropyrimidine-5-carbaldehyde

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2,4-Dichloropyrimidine-5-carbaldehyde

CAS No. 871254-61-4

Recommended Products