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Structure of 871493-04-8
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3-Bromo-6-fluoro-2,4-dimethylpyridine features a sterically hindered pyridine core with complementary halogen handles, enabling selective cross-coupling reactions. The electron-deficient ring facilitates transition-metal-catalyzed transformations, while the methyl groups enhance solubility and stability under standard conditions.
3-Bromo-6-fluoro-2,4-dimethylpyridine serves as a versatile building block for medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromine center facilitates Suzuki, Stille, and Negishi couplings, while the fluorine and methyl groups enhance metabolic stability and modulate electronic properties. Its bench-stable, crystalline form simplifies handling and purification, making it ideal for iterative scaffold diversification in target-oriented synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: