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Structure of 87150-13-8
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4-(Oxazol-5-yl)benzonitrile features a rigid, electron-deficient aromatic core that integrates a nitrile group and a heteroaromatic oxazole moiety. This combination enables efficient coupling in transition-metal-catalyzed reactions and enhances binding affinity in target-directed synthesis. The molecule exhibits robust stability under standard conditions and demonstrates favorable solubility in common organic solvents.
4-(Oxazol-5-yl)benzonitrile serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds through palladium-catalyzed cross-coupling reactions. Its dual functionality—aryl nitrile and oxazole ring—confers high stability, favorable solubility, and compatibility with diverse reaction conditions. The molecule facilitates efficient access to bioactive architectures commonly found in kinase inhibitors and CNS-targeted compounds, offering robust performance in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: