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Structure of 871700-24-2
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This pyrido[2,3-d]pyrimidine derivative features a sterically hindered cyclopropyl group and a fluorinated iodophenyl moiety, enhancing metabolic stability and target affinity. The hydroxy and dimethyl substituents support hydrogen bonding interactions, while the trione scaffold enables robust coordination in kinase inhibition pathways. Bench-stable and compatible with standard synthetic workflows.
3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione serves as a versatile building block for constructing biologically relevant heterocyclic scaffolds. Its iodophenyl group enables palladium-catalyzed cross-coupling reactions, while the hydroxyl and multiple carbonyl functionalities support derivatization via acylation, alkylation, or cyclization. Bench-stable and compatible with standard purification methods, it facilitates efficient synthesis of complex pyrido[2,3-d]pyrimidine-based candidates in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: