(R)-2-Aminopent-4-ynoic acid hydrochloride

Name: (R)-2-Aminopent-4-ynoic acid hydrochloride
Brand: ChemScene
Availability: InStock
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CAS No. 87205-47-8
Cat. No. CS-0158576
Purity≥97%
MDL No.MFCD09263338

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Type	HazMat Fee
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FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(R)-2-Aminopent-4-ynoic acid hydrochloride|CS-0158576

Structure of 87205-47-8

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Description

(R)-2-Aminopent-4-ynoic acid hydrochloride features a chiral α-amino acid scaffold with a terminal alkyne handle, enabling bioorthogonal conjugation in peptide and probe synthesis. The hydrochloride salt enhances solubility and stability under standard bench conditions, facilitating straightforward handling in aqueous and organic media. This derivative integrates efficiently into diverse molecular architectures through click chemistry or amide coupling protocols.

Application

(R)-2-Aminopent-4-ynoic acid hydrochloride serves as a versatile building block for the synthesis of bioactive heterocycles and peptidomimetics. Its terminal alkyne and α-amino carboxylic acid functionalities enable efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) and direct incorporation into peptide chains. The hydrochloride salt enhances bench stability and simplifies handling, while the stereochemically defined (R)-configuration ensures predictable reactivity in asymmetric synthesis.

General Information

CAS No. 87205-47-8
Cat. No. CS-0158576
Purity ≥97%
MDL No. MFCD09263338
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₈ClNO₂
Molecular Weight 149.58
Synonym(s) R-2-Amino-4-Pentynoic acid
SMILES C#CC[C@@H](N)C(O)=O.Cl

Computational Chemistry Data

TPSA 63.32
LogP -0.1566
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Life Science Amino Acids and their Derivatives Glycine and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

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(R)-2-Aminopent-4-ynoic acid hydrochloride

CAS No. 87205-47-8

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