Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-(3,5-Difluorophenyl)ethan-1-ol

  • CAS No. 872181-59-4

  • Cat. No. CS-0149386
  • Purity≥98%
  • MDL No.MFCD04038285

*For research and further manufacturing use only, not for direct human use.

1-(3,5-Difluorophenyl)ethan-1-ol|CS-0149386

Structure of 872181-59-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 872181-59-4
  • Cat. No. CS-0149386
  • Purity ≥98%
  • MDL No. MFCD04038285
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈F₂O
  • Molecular Weight 158.15
  • Synonym(s) 1-(3,5-Difluorophenyl)ethanol
  • SMILES OC(C)C1=CC(F)=CC(F)=C1

Description

1-(3,5-Difluorophenyl)ethan-1-ol features a sterically accessible hydroxyl group flanked by two electron-withdrawing fluorine atoms, enhancing its stability and reactivity in synthetic transformations. This bench-stable phenolic alcohol integrates readily into complex molecular architectures, serving as a key intermediate in pharmaceutical and agrochemical development.

Application

1-(3,5-Difluorophenyl)ethan-1-ol serves as a valuable building block in medicinal chemistry, offering a stable, bench-ready arylalkanol scaffold with enhanced metabolic stability due to fluorine substitution. The primary alcohol functionality enables straightforward derivatization via esterification, etherification, or oxidation to the corresponding aldehyde or carboxylic acid. Its compatibility with standard coupling reactions and tolerance of diverse functional groups make it a practical intermediate for synthesizing fluorinated heterocycles and bioactive molecules.

Synthesis

  • Route1

    References

    • DECODE CHEMISTRY, INC.; SINGH, Jasbir; GURNEY, Mark E. Patent: WO2005/123724 A1, 2005 ; Location in patent: Page/Page column 71 ;
  • Route2
    • In-stock
      3,5-Difluorobenzaldehyde|CS-D1127
      32085-88-4
    • null|null
      75-16-1
    • ~%
    • In-stock
      1-(3,5-Difluorophenyl)ethan-1-ol|CS-0149386
      872181-59-4

    References

    • Pfizer Inc Patent: US6342497 B1, 2002 ; Location in patent: Page column 32 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.0181
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-(3,5-Difluorophenyl)ethan-1-ol sigma1-(3,5-Difluorophenyl)ethan-1-ol manufacturer1-(3,5-Difluorophenyl)ethan-1-ol price1-(3,5-Difluorophenyl)ethan-1-ol structure1-(3,5-Difluorophenyl)ethan-1-ol SDSbuy 1-(3,5-Difluorophenyl)ethan-1-ol1-(3,5-Difluorophenyl)ethan-1-ol supplier1-(3,5-Difluorophenyl)ethan-1-ol uses1-(3,5-Difluorophenyl)ethan-1-ol molecular weightprice of 1-(3,5-Difluorophenyl)ethan-1-ol1-(3,5-Difluorophenyl)ethan-1-ol chemical name formula of 1-(3,5-Difluorophenyl)ethan-1-ol
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label