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CS-W001157 4
Total: USD 88.00

3-Chlorobenzyl alcohol

  • CAS No. 873-63-2

  • Cat. No. CS-W018271
  • Purity≥98%
  • MDL No.MFCD00004632

*For research and further manufacturing use only, not for direct human use.

3-Chlorobenzyl alcohol|CS-W018271

Structure of 873-63-2

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General Information

  • CAS No. 873-63-2
  • Cat. No. CS-W018271
  • Purity ≥98%
  • MDL No. MFCD00004632
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇ClO
  • Molecular Weight 142.58
  • Synonym(s) M-CHLOROBENZYL ALCOHOL; 3-Chlorobenzyl alcohol
  • SMILES ClC1=CC(CO)=CC=C1

Description

3-Chlorobenzyl alcohol features a chlorinated aromatic ring coupled with a primary alcohol handle, enabling straightforward derivatization. The electron-withdrawing chlorine enhances reactivity in nucleophilic substitution processes while maintaining stability under standard bench conditions. This balance of functionality and robustness makes it well-suited for synthetic intermediates in medicinal chemistry and materials science applications.

Application

3-Chlorobenzyl alcohol serves as a versatile building block in synthetic organic chemistry, enabling efficient functionalization via its reactive primary alcohol and electron-withdrawing chloro substituent. It functions as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, offering good bench stability, straightforward purification, and compatibility with standard coupling and oxidation reactions.

Synthesis

  • Route1

    References

    • Zeynizadeh, Behzad; Yahyaei, Saiedeh Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2004 , vol. 59, # 6 p. 704 - 710
  • Route2
    • null|null
      618-46-2
    • ~10%
    • In-stock
      3-Chlorobenzyl alcohol|CS-W018271
      873-63-2

    References

    • Ravikumar; Chandrasekaran, Srinivasan Journal of Organic Chemistry, 1996 , vol. 61, # 3 p. 826 - 830
  • Route3

    References

    • Organic Letters, , vol. 4, # 12 p. 2055 - 2058

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.8323
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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