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Structure of 873697-78-0
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1-(2-Fluoro-3-nitrophenyl)ethanone features a fluorinated aromatic ring paired with a nitro group in the ortho position relative to the ketone, delivering enhanced electrophilicity and stability under standard conditions. This arrangement facilitates efficient coupling reactions in synthetic organic chemistry, particularly in the construction of complex heterocycles and pharmaceutical intermediates.
1-(2-Fluoro-3-nitrophenyl)ethanone serves as a versatile building block in medicinal chemistry, enabling efficient construction of fused heterocycles and substituted aryl scaffolds. Its ortho-fluoro and meta-nitro substituents provide orthogonal reactivity for palladium-catalyzed cross-coupling and selective reduction sequences. The ketone functionality facilitates nucleophilic additions and enolization, while the compound exhibits sufficient bench stability for routine handling and purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: