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Structure of 874289-40-4
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This boronate reagent features a para-methylcarbamoyl group flanking the boronic acid, enhancing solubility and stability. The ortho-fluoro substituent enables efficient cross-coupling under standard conditions, facilitating direct access to substituted biaryl scaffolds in medicinal chemistry workflows.
2-Fluoro-5-(methylcarbamoyl)benzeneboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl architectures. The boronic acid moiety exhibits excellent bench stability and compatibility with diverse functional groups, while the fluorine and methylcarbamoyl substituents provide orthogonal reactivity for downstream derivatization. Its defined electronic profile facilitates predictable coupling outcomes, making it a practical choice for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: