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Structure of 875770-32-4
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Propargyl-PEG4-Tos features a propargyl group linked via a four-ethylene glycol unit to a p-toluenesulfonyl (Tos) leaving group. This bifunctional reagent enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) and facilitates conjugation in bioorthogonal labeling workflows. The PEG spacer provides enhanced solubility and reduced aggregation in aqueous environments.
Propargyl-PEG4-Tos serves as a versatile bifunctional linker for conjugation and polymer chemistry, enabling efficient CuAAC click reactions via its terminal alkyne group. The PEG4 spacer provides enhanced solubility and reduced aggregation, while the tosyl leaving group facilitates nucleophilic substitution under mild conditions. This compound functions reliably in modular synthesis of bioconjugates, functionalized polymers, and surface-tethered molecules with predictable reactivity and excellent bench stability.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: