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Structure of 875781-15-0
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5-Bromo-2-fluoro-3-pyridinecarboxaldehyde features a trifunctional pyridine core with strategically positioned bromo, fluoro, and aldehyde groups. This electron-deficient heterocycle enables direct coupling in cross-coupling reactions and serves as a key intermediate in medicinal chemistry. The aldehyde functionality allows for facile derivatization under mild conditions, while the ortho-halogens support palladium-catalyzed transformations.
5-Bromo-2-fluoro-3-pyridinecarboxaldehyde serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The aldehyde group facilitates nucleophilic additions and condensation reactions, while the fluorine substituent enhances metabolic stability and modulates electronic properties. Bench-stable and readily purified by flash chromatography, it functions effectively in the construction of bioactive scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: