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Structure of 876-27-7
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4-Chlorophenyl acetate is a bench-stable phenolic ester featuring a chlorine-substituted aromatic ring that enhances electronic withdrawal and metabolic stability. This compound serves as a selective acetyl transfer agent in synthetic transformations, particularly useful in protecting group strategies and peptide derivatization workflows where controlled release of acetyl groups is required.
4-Chlorophenyl acetate serves as a stable, bench-ready aryl acetyl protecting group for phenolic hydroxyls. It facilitates selective acetylation in multi-functional systems and enables orthogonal deprotection under mild conditions. The compound exhibits excellent functional group tolerance and is compatible with standard synthetic workflows, including cross-coupling and nucleophilic substitution reactions. Its predictable reactivity makes it a reliable choice for intermediate synthesis in pharmaceutical and agrochemical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: