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Structure of 87600-98-4
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4,6-Dichloropyrimidine-5-carboxylic acid features a rigid pyrimidine core functionalized with two chlorine atoms and a carboxylic acid group, enabling direct incorporation into bioactive molecules. The electron-deficient heterocycle facilitates nucleophilic substitution reactions under mild conditions, while the carboxylic acid offers versatile coupling handles for peptide and macrocycle synthesis. This compound serves as a key building block in medicinal chemistry campaigns targeting kinase inhibitors and antiviral agents.
4,6-Dichloropyrimidine-5-carboxylic acid serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. The dichloro substitution enables selective functionalization at C4 and C6 positions, while the carboxylic acid group facilitates coupling reactions, derivatization, or salt formation. Its stability under standard reaction conditions and compatibility with diverse transformations make it suitable for constructing pyrimidine-based scaffolds commonly found in kinase inhibitors and antiviral agents.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: