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Structure of 876161-05-6
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5-Bromopyrazine-2-carboxylic acid features a brominated pyrazine core with a carboxylic acid group at the 2-position, enabling direct coupling in cross-coupling reactions. This electron-deficient heterocycle integrates readily into pharmaceutical scaffolds and functional materials, offering enhanced reactivity and stability under standard conditions.
5-Bromopyrazine-2-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromo and carboxylic acid functionalities. The molecule exhibits bench stability and facilitates efficient derivatization via amide formation or esterification, supporting applications in medicinal chemistry and API development. Its orthogonally reactive groups allow sequential functionalization in complex molecule assembly.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: