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CS-W001157 4
Total: USD 88.00

trans-4-[4-(Cyclopropylmethyl)piperazin-1-yl]cyclohexanamine

  • CAS No. 876461-31-3

  • Cat. No. CS-B0208
  • Purity≥98%
  • MDL No.MFCD13184577

*For research and further manufacturing use only, not for direct human use.

trans-4-[4-(Cyclopropylmethyl)piperazin-1-yl]cyclohexanamine|CS-B0208

Structure of 876461-31-3

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General Information

  • CAS No. 876461-31-3
  • Cat. No. CS-B0208
  • Purity ≥98%
  • MDL No. MFCD13184577
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₇N₃
  • Molecular Weight 237.38
  • Synonym(s) trans-4-[4-(Cyclopropylmethyl)piperazin-1-yl]cyclohexanamin
  • SMILES N[C@@H]1CC[C@H](CC1)N(CC2)CCN2CC3CC3

Synthesis

  • Route1
    • (1r,4r)-N,N-Dibenzyl-4-(4-(cyclopropylmethyl)piperazin-1-yl)cyclohexan-1-amine|CS-1356596
      755039-89-5
    • ~98%
    • trans-4-[4-(Cyclopropylmethyl)piperazin-1-yl]cyclohexanamine|CS-B0208
      876461-31-3

    References

    • SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.; JIANGSU HENGRUI MEDICINE CO., LTD. Patent: US2012/184543 A1, 2012 ; Location in patent: Page/Page column 50 ;
  • Route2

    References

    • BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG Patent: WO2006/18182 A1, 2006 ; Location in patent: Page/Page column 73 ; WO 2006/018182 A1 Title/Abstract Full Text Show Details BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG Patent: WO2006/18185 A2, 2006 ; Location in patent: Page/Page column 73 ; WO 2006/018185 A2
  • Route3
    • N-[trans-4-[4-(Cyclopropylmethyl)-1-piperazinyl]cyclohexyl]acetamide|CS-M1205
      882660-40-4
    • ~88%
    • trans-4-[4-(Cyclopropylmethyl)piperazin-1-yl]cyclohexanamine|CS-B0208
      876461-31-3

    References

    • BOEHRINGER INGELHEIM INTERNATIONAL GMBH; Schnaubelt, Juergen; Herter, Rolf Patent: US2012/238754 A1, 2012 ; Location in patent: Paragraph 0100; 0101; 0102 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   32.5
  • LogP   1.2839
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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