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CS-W001157 4
Total: USD 88.00

2,4,6-trimethoxy-1,3,5-triazine

  • CAS No. 877-89-4

  • Cat. No. CS-0197990
  • Purity≥98%
  • MDL No.MFCD00142809

*For research and further manufacturing use only, not for direct human use.

2,4,6-trimethoxy-1,3,5-triazine|CS-0197990

Structure of 877-89-4

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General Information

  • CAS No. 877-89-4
  • Cat. No. CS-0197990
  • Purity ≥98%
  • MDL No. MFCD00142809
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉N₃O₃
  • Molecular Weight 171.15
  • Synonym(s) 2,4,6-trimethoxy-triazine
  • SMILES COC1=NC(OC)=NC(OC)=N1

Description

tert-Nitrosobutane dimer is used as a spin trapping reagent in electron spin resonance studies. Spin trap reagent, Reactant involved in the synthesis of air-stable π-radical based on Corannulene.

Application

2,4,6-Trimethoxy-1,3,5-triazine serves as a versatile bench-stable reagent for mild, selective activation of nucleophiles in amide and ester bond formation. Its methoxy groups enhance solubility and facilitate clean byproduct removal, enabling efficient coupling under ambient conditions. Functions reliably in peptide synthesis and heterocycle functionalization, offering excellent functional group tolerance and compatibility with sensitive substrates.

Synthesis

  • Route1
    • null|null
      108-77-0
    • ~%
    • In-stock
      2,4,6-trimethoxy-1,3,5-triazine|CS-0197990
      877-89-4

    References

    • US2002/123627 A1, ;
  • Route2
    • null|null
      675-14-9
    • ~75%
    • In-stock
      2,4,6-trimethoxy-1,3,5-triazine|CS-0197990
      877-89-4

    References

    • Grisley et al. Journal of Organic Chemistry, 1958 , vol. 23, p. 1802 Full Text View citing articles Show Details Gmelin Handbook: C: MVol.D3, 7.1.4.3, page 272 - 272
  • Route3
    • null|null
      67-56-1
    • null|null
      108-77-0
    • ~66%
    • In-stock
      2,4,6-trimethoxy-1,3,5-triazine|CS-0197990
      877-89-4

    References

    • Nedel'ko; Shastin; Korsunskii; Chukanov; Larikova; Kazakov Russian Chemical Bulletin, 2005 , vol. 54, # 7 p. 1710 - 1714

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.36
  • LogP   -0.1026
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   3

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