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Structure of 877264-44-3
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5-Fluoro-2-iodobenzaldehyde is a halogenated aromatic aldehyde featuring fluorine and iodine substituents at meta and ortho positions relative to the aldehyde group. This electron-deficient scaffold enables direct functionalization in cross-coupling reactions, offering enhanced reactivity and selectivity in transition metal-catalyzed transformations. The molecule exhibits bench-stable handling characteristics and compatibility with diverse reaction conditions.
5-Fluoro-2-iodobenzaldehyde serves as a versatile building block in transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The ortho-iodo group facilitates palladium-catalyzed coupling with boronic acids, esters, and amines, while the aldehyde functionality permits further derivatization via reductive amination or nucleophilic addition. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for modular synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: